Claudin 1 Antikörper
Kurzübersicht für Claudin 1 Antikörper (ABIN2460770)
Target
Alle Claudin 1 (CLDN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN1.
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Applikationshinweise
- CLDN1 antibody can be used for detection of CLDN1 by ELISA at 1:312500. CLDN1 antibody can be used for detection of CLDN1 by western blot at 1.0-5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Konzentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store CLDN1 antibody at -20 °C.
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- Claudin 1 (CLDN1)
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Andere Bezeichnung
- CLDN1
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Hintergrund
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.
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Molekulargewicht
- 23 kDa
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Gen-ID
- 9076
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NCBI Accession
- NP_066924
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UniProt
- O95832
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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