POU4F3 Antikörper
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- Target Alle POU4F3 Antikörper anzeigen
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
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Reaktivität
- Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POU4F3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU4F3.
- Top Product
- Discover our top product POU4F3 Primärantikörper
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- Applikationshinweise
- POU4F3 antibody can be used for detection of POU4F3 by ELISA at 1:312500. POU4F3 antibody can be used for detection of POU4F3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU4F3 antibody at -20 °C.
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- Target
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
- Andere Bezeichnung
- POU4F3 (POU4F3 Produkte)
- Synonyme
- POU4F3 antikoerper, BRN-3 antikoerper, BRN3 antikoerper, BRN3C antikoerper, DFNA15 antikoerper, BRN-3.1 antikoerper, brn-3c antikoerper, brn3.1 antikoerper, brn3c antikoerper, Brn3.1 antikoerper, Brn3c antikoerper, ddl antikoerper, dreidel antikoerper, POU class 4 homeobox 3 antikoerper, POU domain, class 4, transcription factor 3 antikoerper, POU4F3 antikoerper, Pou4f3 antikoerper, pou4f3 antikoerper
- Hintergrund
- POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
- Molekulargewicht
- 37 kDa
- Gen-ID
- 5459
- NCBI Accession
- NP_002691
- UniProt
- Q15319
- Pathways
- Sensory Perception of Sound
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