POU4F3 Antikörper

Produktnummer ABIN2460646

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch POU4F3 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund und Zebrafisch (Danio rerio).

Kurzübersicht für POU4F3 Antikörper (ABIN2460646)

Target: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU4F3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-POU4F3 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU4F3.

Anwendungsinformationen

Applikationshinweise: POU4F3 antibody can be used for detection of POU4F3 by ELISA at 1:312500. POU4F3 antibody can be used for detection of POU4F3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store POU4F3 antibody at -20 °C.

Details zu POU4F3

Target: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Andere Bezeichnung: POU4F3

Hintergrund: POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.

Molekulargewicht: 37 kDa

Gen-ID: 5459

NCBI Accession: NP_002691

UniProt: Q15319

Pathways: Sensory Perception of Sound