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REXO4 Antikörper

Dieses Anti-REXO4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von REXO4 in ELISA und WB. Geeignet für Human, Ratte, Maus und Hund.
Produktnummer ABIN2460618

Kurzübersicht für REXO4 Antikörper (ABIN2460618)

Target

Alle REXO4 Antikörper anzeigen
REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Reaktivität

  • 14
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus, Hund

Wirt

  • 13
  • 1
Kaninchen

Klonalität

  • 14
Polyklonal

Konjugat

  • 10
  • 2
  • 1
  • 1
Dieser REXO4 Antikörper ist unkonjugiert

Applikation

  • 9
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB)
  • Aufreinigung

    Antibody is purified by peptide affinity chromatography method.

    Immunogen

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REXO4.
  • Applikationshinweise

    REXO4 antibody can be used for detection of REXO4 by ELISA at 1:1562500. REXO4 antibody can be used for detection of REXO4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Konzentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Handhabung

    As with any antibody avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store REXO4 antibody at -20 °C.
  • Target

    REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

    Andere Bezeichnung

    REXO4

    Hintergrund

    The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.

    Molekulargewicht

    47 kDa

    Gen-ID

    57109

    NCBI Accession

    NP_065118

    UniProt

    Q9GZR2
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