SMAD6 Antikörper
Kurzübersicht für SMAD6 Antikörper (ABIN2460536)
Target
Alle SMAD6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Antibody is supplied as total IgG.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD6.
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Applikationshinweise
- SMAD6 antibody can be used for detection of SMAD6 by ELISA at 1:62500. SMAD6 antibody can be used for detection of SMAD6 by western blot at 0.5-1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 200 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Konzentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMAD6 antibody at -20 °C.
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- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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Andere Bezeichnung
- SMAD6
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Hintergrund
- SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
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Molekulargewicht
- 53 kDa
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Gen-ID
- 4091
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NCBI Accession
- NP_005576
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UniProt
- O43541
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Pathways
- Chromatin Binding
Target
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