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SMAD6 Antikörper

Der Kaninchen Polyklonal Anti-SMAD6-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, SMAD6 in Proben von Human, Maus, Ratte und Hund zu detektieren.
Produktnummer ABIN2460536

Kurzübersicht für SMAD6 Antikörper (ABIN2460536)

Target

Alle SMAD6 Antikörper anzeigen
SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Reaktivität

  • 46
  • 22
  • 11
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
Human, Maus, Ratte, Hund

Wirt

  • 46
  • 14
Kaninchen

Klonalität

  • 48
  • 12
Polyklonal

Konjugat

  • 43
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SMAD6 Antikörper ist unkonjugiert

Applikation

  • 52
  • 29
  • 16
  • 11
  • 8
  • 7
  • 6
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Aufreinigung

    Antibody is supplied as total IgG.

    Immunogen

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD6.
  • Applikationshinweise

    SMAD6 antibody can be used for detection of SMAD6 by ELISA at 1:62500. SMAD6 antibody can be used for detection of SMAD6 by western blot at 0.5-1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 200 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Konzentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Handhabung

    As with any antibody avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMAD6 antibody at -20 °C.
  • Target

    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

    Andere Bezeichnung

    SMAD6

    Hintergrund

    SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.

    Molekulargewicht

    53 kDa

    Gen-ID

    4091

    NCBI Accession

    NP_005576

    UniProt

    O43541

    Pathways

    Chromatin Binding
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