KAT2B Antikörper

Produktnummer ABIN2460477

Produktdetails anti-KAT2B Antikörper

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Reaktivität: Human, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCAF.

Anwendungsinformationen

Applikationshinweise: PCAF antibody can be used for detection of PCAF by ELISA at 1:62500. PCAF antibody can be used for detection of PCAF by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCAF antibody at -20 °C.

Details zu KAT2B

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Andere Bezeichnung: PCAF (KAT2B Produkte)

Synonyme: PCAF antikoerper, pcaf antikoerper, si:ch211-1j13.2 antikoerper, zgc:161980 antikoerper, gb:dq017634 antikoerper, im:7156024 antikoerper, CAF antikoerper, P antikoerper, P/CAF antikoerper, A930006P13Rik antikoerper, AI461839 antikoerper, AW536563 antikoerper, Pcaf antikoerper, p/CAF antikoerper, lysine acetyltransferase 2B antikoerper, K(lysine) acetyltransferase 2B antikoerper, K(lysine) acetyltransferase 2A antikoerper, KAT2B antikoerper, kat2b antikoerper, kat2a antikoerper, Kat2b antikoerper

Hintergrund: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Molekulargewicht: 93 kDa

Gen-ID: 8850

NCBI Accession: NP_003875

UniProt: Q92831

Pathways: p53 Signalweg, Regulation of Carbohydrate Metabolic Process