ETV5 Antikörper

Produktnummer ABIN2460409

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ETV5 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Hund.

Kurzübersicht für ETV5 Antikörper (ABIN2460409)

Target: ETV5 (Ets Variant 5 (ETV5))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ETV5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ETV5 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ETV5.

Anwendungsinformationen

Applikationshinweise: ETV5 antibody can be used for detection of ETV5 by ELISA at 1:62500. ETV5 antibody can be used for detection of ETV5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ETV5 antibody at -20 °C.

Details zu ETV5

Target: ETV5 (Ets Variant 5 (ETV5))

Andere Bezeichnung: ETV5

Hintergrund: ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer

Molekulargewicht: 58 kDa, 58 kDa

Gen-ID: 2119

NCBI Accession: NP_004445

UniProt: P41161

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development