ALAS1 Antikörper

Produktnummer ABIN2459736

Dieses Anti-ALAS1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ALAS1 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ALAS1 Antikörper (ABIN2459736)

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ALAS1 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALAS1.

Anwendungsinformationen

Applikationshinweise: ALAS1 antibody can be used for detection of ALAS1 by ELISA at 1:312500. ALAS1 antibody can be used for detection of ALAS1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ALAS1 antibody at -20 °C.

Details zu ALAS1

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Andere Bezeichnung: ALAS1

Hintergrund: Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.

Molekulargewicht: 70 kDa

Gen-ID: 211

NCBI Accession: NP_000679

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha