Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Klotho beta Antikörper

KLB Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2459659
  • Target Alle Klotho beta (KLB) Antikörper anzeigen
    Klotho beta (KLB)
    Reaktivität
    • 16
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 22
    • 1
    Kaninchen
    Klonalität
    • 22
    • 1
    Polyklonal
    Konjugat
    • 13
    • 7
    • 2
    • 1
    Dieser Klotho beta Antikörper ist unkonjugiert
    Applikation
    • 18
    • 13
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KLB.
    Top Product
    Discover our top product KLB Primärantikörper
  • Applikationshinweise
    KLB antibody can be used for detection of KLB by ELISA at 1:12500. KLB antibody can be used for detection of KLB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store KLB antibody at -20 °C.
  • Target
    Klotho beta (KLB)
    Andere Bezeichnung
    KLB (KLB Produkte)
    Synonyme
    KLB antikoerper, BKL antikoerper, AV071179 antikoerper, betaKlotho antikoerper, Klb-ps1 antikoerper, RGD1308227 antikoerper, klotho beta antikoerper, KLB antikoerper, Klb antikoerper
    Hintergrund
    KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
    Molekulargewicht
    120 kDa
    Gen-ID
    152831
    NCBI Accession
    NP_783864
    UniProt
    Q86Z14
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Growth Factor Binding
Sie sind hier:
Kundenservice