SPTLC2 Antikörper

Produktnummer ABIN2459217

Produktdetails anti-SPTLC2 Antikörper

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTLC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPTLC2.

Anwendungsinformationen

Applikationshinweise: SPTLC2 antibody can be used for detection of SPTLC2 by ELISA at 1:312500. SPTLC2 antibody can be used for detection of SPTLC2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPTLC2 antibody at -20 °C.

Details zu SPTLC2

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Andere Bezeichnung: SPTLC2 (SPTLC2 Produkte)

Synonyme: HSN1C antikoerper, LCB2 antikoerper, LCB2A antikoerper, NSAN1C antikoerper, SPT2 antikoerper, hLCB2a antikoerper, sptlc2 antikoerper, zgc:110661 antikoerper, AI173915 antikoerper, mKIAA0526 antikoerper, Pomt2 antikoerper, LCB2a antikoerper, SPTLC2 antikoerper, serine palmitoyltransferase long chain base subunit 2 antikoerper, serine palmitoyltransferase 2 antikoerper, serine palmitoyltransferase, long chain base subunit 2 S homeolog antikoerper, serine palmitoyltransferase, long chain base subunit 2a antikoerper, serine palmitoyltransferase, long chain base subunit 2 antikoerper, SPTLC2 antikoerper, LOC100446763 antikoerper, sptlc2 antikoerper, sptlc2.S antikoerper, sptlc2a antikoerper, Sptlc2 antikoerper

Hintergrund: SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.

Molekulargewicht: 63 kDa

Gen-ID: 9517

NCBI Accession: NP_004854

UniProt: O15270