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POMT1 Antikörper

POMT1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2458911
  • Target Alle POMT1 Antikörper anzeigen
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    Reaktivität
    • 43
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 44
    Kaninchen
    Klonalität
    • 44
    Polyklonal
    Konjugat
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POMT1 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 19
    • 17
    • 16
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POMT1.
    Top Product
    Discover our top product POMT1 Primärantikörper
  • Applikationshinweise
    POMT1 antibody can be used for detection of POMT1 by ELISA at 1:62500. POMT1 antibody can be used for detection of POMT1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store POMT1 antibody at -20 °C.
  • Target
    POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))
    Andere Bezeichnung
    POMT1 (POMT1 Produkte)
    Synonyme
    LGMD2K antikoerper, MDDGA1 antikoerper, MDDGB1 antikoerper, MDDGC1 antikoerper, RT antikoerper, AI505244 antikoerper, protein O-mannosyltransferase 1 antikoerper, protein-O-mannosyltransferase 1 antikoerper, POMT1 antikoerper, Pomt1 antikoerper
    Hintergrund
    POMT1 is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K).O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. POMT1 shares sequence similarity with protein O-mannosyltransferases of S. cerevisiae. In yeast, these enzymes are located in the endoplasmic reticulum (ER) and are required for cell integrity and cell wall rigidity. POMT1 also shows similarity to the Drosophila 'rotated abdomen' (rt) gene, which when mutated causes defects in myogenesis and muscle structure.
    Molekulargewicht
    82 kDa
    Gen-ID
    10585
    NCBI Accession
    NP_001070833
    UniProt
    B3KQG0
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