EYA1 Antikörper

Produktnummer ABIN2457953

Der Kaninchen Polyklonal Anti-EYA1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, EYA1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für EYA1 Antikörper (ABIN2457953)

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EYA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-EYA1 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EYA1.

Anwendungsinformationen

Applikationshinweise: EYA1 antibody can be used for detection of EYA1 by ELISA at 1:312500. EYA1 antibody can be used for detection of EYA1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EYA1 antibody at -20 °C.

Details zu EYA1

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Andere Bezeichnung: EYA1

Hintergrund: EYA1 is a member of the eyes absent (EYA) family of proteins. EYA1 may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator.This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.

Molekulargewicht: 61 kDa

Gen-ID: 2138

NCBI Accession: NP_742057

UniProt: Q99502

Pathways: Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus