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NUP98 Antikörper (AA 1-466)

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch NUP98 in WB, ELISA, IF, ICC und DB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Saccharomyces cerevisiae und Schizosaccharomyces pombe und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN2452066

Kurzübersicht für NUP98 Antikörper (AA 1-466) (ABIN2452066)

Target

Alle NUP98 Antikörper anzeigen
NUP98 (Nucleoporin 98kDa (NUP98))

Reaktivität

  • 54
  • 19
  • 14
  • 8
  • 6
  • 6
  • 6
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Saccharomyces cerevisiae, Schizosaccharomyces pombe

Wirt

  • 45
  • 12
Ratte

Klonalität

  • 42
  • 15
Monoklonal

Konjugat

  • 47
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NUP98 Antikörper ist unkonjugiert

Applikation

  • 44
  • 18
  • 17
  • 13
  • 8
  • 7
  • 3
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

Klon

2H10
  • Bindungsspezifität

    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-466

    Kreuzreaktivität (Details)

    This antibody does not react with Tetrahymena.
    Other species have not been tested.

    Aufreinigung

    Purified

    Sterilität

    Sterile filtered

    Immunogen

    Recombinant GST-fused human Nup98 (aa 1-466)

    Isotyp

    IgG2c kappa
  • Applikationshinweise

    1) Western blotting
    2) Immunocytochemistry
    3) ELISA
    4) Dot blotting

    Properties:
    When injected into the cytoplasm, this antibody accumulates into the nuclear pores of HeLa cells and inhibits nuclear localization of endogenous Ran.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS, 50 % glycerol. Azide- and carrier protein-free.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Upon arrival centrifuge briefly and store at -20 C.
  • Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).

    Fukuhara, Ozaki, Shikata, Katahira, Yoneda, Ogino, Tachibana: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." in: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).

  • Target

    NUP98 (Nucleoporin 98kDa (NUP98))

    Andere Bezeichnung

    Nup98

    Hintergrund

    Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export. Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. This hybridoma has been established by Prof. T. Tachibana's Lab. at Osaka City Univ.

    UniProt

    Q9HDC8

    Pathways

    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interaktom
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