NUP153 Antikörper (AA 610-1191)

Produktnummer ABIN2452062

Dieses Anti-NUP153-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von NUP153 in WB, ELISA, IF und ICC. Geeignet für Ratte. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für NUP153 Antikörper (AA 610-1191) (ABIN2452062)

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Reaktivität: Ratte

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser NUP153 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: R4C8

Produktdetails anti-NUP153 Antikörper

Bindungsspezifität: AA 610-1191

Spezifität: Specific to human, mouse, rat and monkey Nup153 proteins.

Kreuzreaktivität (Details): Not tested for other species

Produktmerkmale: When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.

Aufreinigung: Purified

Sterilität: Sterile filtered

Immunogen: Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: 1. Western blotting: 160 kDa single band in Hela cell extract
2. Immunocytochemistry
3. ELISA
Other applications have not been tested.

Additional comments:
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt aliquot and store at -20 C

Referenzen für anti-NUP153 Antikörper (ABIN2452062)

Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).

Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).

Details zu NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Andere Bezeichnung: Nup153

Hintergrund: The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.

UniProt: P49790

Pathways: Protein targeting to Nucleus