NOB1 Antikörper

Produktnummer ABIN2452059

Dieses Anti-NOB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NOB1 in WB und IP. Geeignet für Saccharomyces cerevisiae. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für NOB1 Antikörper (ABIN2452059)

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Reaktivität: Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-NOB1 Antikörper

Produktmerkmale: Product: Rabbit polyclonal antibody affinity purified with recombinant Nob1p

Aufreinigung: Affinity purified

Immunogen: Recombinant yeast Nob1p expressed in E. coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1) Western blotting: ~400 fold dilution
2) Immunoprecipitation Not tested for other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 1 mg/mL BSA as carrier, 0.09 % sodium azide, 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-NOB1 Antikörper (ABIN2452059)

Tone, Toh-E: "Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae." in: Genes & development, Vol. 16, Issue 24, pp. 3142-57, (2002) (PubMed).

Tone, Tanahashi, Tanaka, Fujimuro, Yokosawa, Toh-e: "Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells." in: Gene, Vol. 243, Issue 1-2, pp. 37-45, (2000) (PubMed).

Details zu NOB1

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Andere Bezeichnung: Nob1

Hintergrund: Background: The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Nob1p is essential nuclear protein required for biogenesis of the 26S proteasome. Nob1p is speculated to serve as a chaperone to join the 20S proteasome with the 19S regulatory particle in the nucleus and to be degraded upon the maturation of the 26S proteasome. Nob1p is composed of 459 amino acid residues.

Pathways: Protein targeting to Nucleus