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Nestin Antikörper

Dieses Anti-Nestin-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Nestin in IHC und ICC. Geeignet für Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN2452056

Kurzübersicht für Nestin Antikörper (ABIN2452056)

Target

Alle Nestin (NES) Antikörper anzeigen
Nestin (NES)

Reaktivität

  • 128
  • 41
  • 36
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Maus

Wirt

  • 76
  • 65
  • 3
  • 1
Ratte

Klonalität

  • 73
  • 72
Monoklonal

Konjugat

  • 89
  • 8
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Nestin Antikörper ist unkonjugiert

Applikation

  • 77
  • 75
  • 43
  • 41
  • 37
  • 34
  • 24
  • 20
  • 14
  • 13
  • 12
  • 10
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon

7A3
  • Spezifität

    Specific to mouse Nestin.

    Kreuzreaktivität (Details)

    Not tested in other species.

    Produktmerkmale

    The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.

    Aufreinigung

    Purified

    Sterilität

    Sterile filtered

    Immunogen

    Mouse E16 embryonic cerebral cortex extracts

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    1. Immunocytochemistry
    2. Immunohistochemistry
    This antibody doesn't work in immunoblotting.
    Other applications are not tested.

    This antibody is very useful for immunostaining of mouse embryonic brain because it is rat antibody. Rat antibody has very low background in immunostaining using mouse tissues and is also useful for double-staining with mouse and rabbit antibodies.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS, 50 % glycerol

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C
  • Gilyarov: "Nestin in central nervous system cells." in: Neuroscience and behavioral physiology, Vol. 38, Issue 2, pp. 165-9, (2008) (PubMed).

    Hockfield, McKay: "Identification of major cell classes in the developing mammalian nervous system." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 5, Issue 12, pp. 3310-28, (1986) (PubMed).

  • Target

    Nestin (NES)

    Andere Bezeichnung

    Nestin

    Hintergrund

    Nestin is an intermediate filament protein that is expressed in stem cells and progenitor cells in the mammalian central nervous system (CNS) during development. Nestin is replaced in the adult organism by other intermediate filament proteins, however, it may be re-expressed under certain pathological conditions such as ischemia, inflammation, brain injury, and neoplastic transformation. Nestin has been detected in many kinds of tumors, especially in tumors derived from the CNS, therefore it is considered to be a marker for cancer stem cells in neurogenic tumors.

    UniProt

    Q6P5H2
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