tau Antikörper (pThr217)

Produktnummer ABIN2443974

Der Kaninchen Polyklonal anti-tau Antikörper (ABIN2443974) detektiert spezifisch tau in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für tau Antikörper (pThr217) (ABIN2443974)

Target: tau (tau Protein)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser tau Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-tau Antikörper

Bindungsspezifität: pThr217

Verwendungszweck: Phospho-Tau (thr 217) Rabbit Polyclonal Antibody

Spezifität: The antibody recognizes the human Phospho-Tau protein peptide at the Threonine 217 (Thr 217) phosphorylation site. (MW 48-67 kDa)

Aufreinigung: Immunogen affinity purified

Immunogen: Peptide phosphorylated at Thr 217

Anwendungsinformationen

Applikationshinweise: IHC 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: If reconstituted with deionized water in 50 μL: WB: 1:10000, IHC 1:1000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized immunogen affinity purified in PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Haltbarkeit: 24 months

Details zu tau

Target: tau (tau Protein)

Andere Bezeichnung: tau

Hintergrund: Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of tau protein. Furthermore, these accumulated tau proteins all display an abnormal phosphorylation pattern that may be disease specific. As an example, Amyotrophic lateral sclerosis (ALS, also referred to as Charcot's disease or Lou Gehrig's disease) is the most common form of progressive motor neuron disease in North America. ALS gradually disables the patient's voluntary motor muscle control until it becomes fatal.

UniProt: P10636