Enkephalin Antikörper (N-Term)

Produktnummer ABIN2443860

Der Kaninchen Polyklonal anti-Enkephalin Antikörper (ABIN2443860) detektiert spezifisch Enkephalin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Säugetier und Rind (Kuh).

Kurzübersicht für Enkephalin Antikörper (N-Term) (ABIN2443860)

Target: Enkephalin (PENK) (Proenkephalin (PENK))

Reaktivität: Säugetier, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Enkephalin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Enkephalin Antikörper

Bindungsspezifität: AA 63-70, N-Term

Verwendungszweck: Proenkephalin-A (N-term) Rabbit Polyclonal Antibody

Spezifität: The antibody recognizes an epitope in N-terminal (AA 63-70) of Proenkephalin A

Immunogen: N-terminal peptide (AA 63-70)

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: If reconstituted with deionized water in 100 μL: WB 1:1000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Haltbarkeit: 24 months

Details zu Enkephalin

Target: Enkephalin (PENK) (Proenkephalin (PENK))

Andere Bezeichnung: Proenkephalin-A

Hintergrund:

Proenkephalin (PENK), PEA

Vertebrate endogenous opioid neuropeptides are released by post-translational proteolytic cleavage of precursor proteins. Proenkephalin-A is one of the three opioid neuropeptide precursor molecules of the opioid pentapeptides Met- and Leu-enkephalin, which compete with and mimic the effects of opiate drugs. Upon cleavage, each proenkephalin peptide results in the generation of four copies of Met-enkephalin, two extended copies of Met-enkephalin, and one copy of Leu-enkephalin. Proenkephalin opioid neuropeptide is one of the key neurobiological substrates of addiction disorders implicated in reward, mood regulation, stress response, and motor function.

UniProt: P01211

Pathways: Stem Cell Maintenance