CAN Antikörper (small, Subunit B)

Produktnummer ABIN2443839

Der Maus Monoklonal anti-CAN Antikörper (Klon VA1) (ABIN2443839) detektiert spezifisch CAN in WB, IHC, IP, ELISA und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte, Rind (Kuh) und Kaninchen.

Kurzübersicht für CAN Antikörper (small, Subunit B) (ABIN2443839)

Target: CAN (Calcineurin (CAN))

Reaktivität: Ratte, Rind (Kuh), Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CAN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunocytochemistry (ICC)

Klon: VA1

Produktdetails anti-CAN Antikörper

Bindungsspezifität: small, Subunit B

Verwendungszweck: Calcineurin Mouse Monoclonal Antibody (VA1)

Spezifität: The antibody recognizes the regulatory β-subunit of calcineurin

Aufreinigung: Protein G purified

Immunogen: Full lenght bovine protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: If reconstituted with deionized water in 100 μL: WB: 1:2000, ICC: 1:200. Optimal dilution has to be determined by the user.

Buffer: Lyophilized protein G purified in PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Haltbarkeit: 24 months

Details zu CAN

Target: CAN (Calcineurin (CAN))

Andere Bezeichnung: Calcineurin

Hintergrund:

Calcineurin beta-subunit

Within the last 30 years of research the biological roles of calcineurin have progressed from a putative inhibitor of the calmodulin dependent phosphodiesterase to the ground-breaking discovery that it is the target of immunosuppressant drugs such as cyclosporin A. As a serine/threonine protein phosphatase, calcineurin participates in a number of cellular processes and Ca2+ dependent signal transduction pathways. Calcineurin plays a key role in regulating the transcription factor NF-AT during T-cell activation, and in mediating responses of microorganisms to cation stress. Recently, this protein was studied extensively in relation to diseases such as schizophrenia and diabetes.

UniProt: P63099