RAP1GDS1 Antikörper
Kurzübersicht für RAP1GDS1 Antikörper (ABIN2443838)
Target
Alle RAP1GDS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- RAP1GDS1 Rabbit Polyclonal Antibody
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Spezifität
- The antibody recognizes the human RAP1GDS1 protein.
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Applikationshinweise
- WB 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- If reconstituted with deionized water in 100 μL: WB 1:1000 - 1:3000. Optimal dilution has to be determined by the user.
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Buffer
- Lyophilized serum
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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Haltbarkeit
- 24 months
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- RAP1GDS1 (RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1))
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Andere Bezeichnung
- RAP1GDS1
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Hintergrund
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Rap1 GTPase-GDP dissociation stimulator 1, Exchange factor smgGDS, SMG GDS protein, SMG P21 stimulatory GDP/GTP exchange protein
Small G-protein dissociation stimulator (Smg-GDS) is a guanine nucleotide exchange factor which displays a wide variety of target proteins both from the Ras and Rho families. Small GTPases are known for their ability to bind GTP and hydrolyze the bound GTP to GDP. SmgGDS has been shown to be upregulated in several types of cancer such as non-small cell lung carcinoma and prostate cancer, where it promotes both proliferation and migration.
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UniProt
- P52306
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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