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NAIF1 Antikörper

NAIF1 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2428455
  • Target Alle NAIF1 Antikörper anzeigen
    NAIF1 (Nuclear Apoptosis Inducing Factor 1 (NAIF1))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 25
    • 1
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NAIF1 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Recombinant protein of human NAIF1
    Isotyp
    IgG
    Top Product
    Discover our top product NAIF1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Handhabung
    Avoid freeze / thaw cycles.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C (regular) and -80°C (long term).
  • Target
    NAIF1 (Nuclear Apoptosis Inducing Factor 1 (NAIF1))
    Andere Bezeichnung
    NAIF1 (NAIF1 Produkte)
    Hintergrund
    Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
    Synonyms: C9orf90, bA379C10.2, RP11-379C10.2
    Molekulargewicht
    Calculated MW: 35 kDa
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