NAIF1 Antikörper

Produktnummer ABIN2428455

Dieser Anti-NAIF1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von NAIF1 in ELISA, WB und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für NAIF1 Antikörper (ABIN2428455)

Target: NAIF1 (Nuclear Apoptosis Inducing Factor 1 (NAIF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAIF1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NAIF1 Antikörper

Aufreinigung: Antigen affinity purification

Immunogen: Recombinant protein of human NAIF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C (regular) and -80°C (long term).

Details zu NAIF1

Target: NAIF1 (Nuclear Apoptosis Inducing Factor 1 (NAIF1))

Andere Bezeichnung: NAIF1

Hintergrund: Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
Synonyms: C9orf90, bA379C10.2, RP11-379C10.2

Molekulargewicht: Calculated MW: 35 kDa