Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Avoid freeze / thaw cycles.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Store at -20°C (regular) and -80°C (long term).
Target
NFKBIL2
(Tonsoku-Like, DNA Repair Protein (NFKBIL2))
Andere Bezeichnung
TONSL
Hintergrund
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. Synonyms: IKBR, NFKBIL2