Der Kaninchen Polyklonal Anti-VMP1-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, VMP1 in Proben von Human, Maus und Ratte zu detektieren.
VMP1
Reaktivität: Human
WB, IF, ICC
Wirt: Kaninchen
Polyclonal
APC
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Avoid freeze / thaw cycles.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Store at -20°C (regular) and -80°C (long term).
Target
VMP1
(Vacuole Membrane Protein 1 (VMP1))
Andere Bezeichnung
VMP1
Hintergrund
VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation. Synonyms: EPG3, TANGO5, TMEM49