Der Kaninchen Polyklonal anti-VMP1 Antikörper wird verwendet zum Nachweis von VMP1 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA und IHC.
VMP1
Reaktivität: Human
WB, ICC, IF
Wirt: Kaninchen
Polyclonal
Atto 594
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Avoid freeze / thaw cycles.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Store at -20°C (regular) and -80°C (long term).
Target
VMP1
(Vacuole Membrane Protein 1 (VMP1))
Andere Bezeichnung
VMP1
Hintergrund
VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation. Synonyms: EPG3, TANGO5, TMEM49