Der Kaninchen Polyklonal anti-TGFBR1 Antikörper (ABIN2426967) detektiert spezifisch TGFBR1 in ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.