FAM107A Antikörper

Produktnummer ABIN2423423

Produktdetails anti-FAM107A Antikörper

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM107A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human FAM107A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FAM107A

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Andere Bezeichnung: FAM107A (FAM107A Produkte)

Synonyme: drr1 antikoerper, tu3a antikoerper, xdrr1 antikoerper, DRR1 antikoerper, TU3A antikoerper, Drr1 antikoerper, RGD1306327 antikoerper, Tu3a antikoerper, family with sequence similarity 107 member A S homeolog antikoerper, family with sequence similarity 107 member A antikoerper, family with sequence similarity 107, member A antikoerper, fam107a.S antikoerper, FAM107A antikoerper, Fam107a antikoerper

Hintergrund: FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.