CD300a Antikörper (PE)

Produktnummer ABIN238466

Produktdetails anti-CD300a Antikörper (PE)

Target: CD300a (CD300A)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD300a Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: The antibody reacts with CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25 % of circulating T cells and 15 % of circulating B cells.

Produktmerkmale: Synonyms: CLM-8, CMRF35-H, CMRF35-H9, CMRF-35-H9, IRC1/IRC2, IRp60, CMRF35-like molecule 8,Inhibitory receptor protein 60, NK inhibitory receptor, CD300 antigen-like family member A

Aufreinigung: Size-Exclusion Chromatography.

Immunogen: HPB human acute lymphoid leukemia cell line

Klon: MEM-260

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL ofwhole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody in the dark at 2-8 °C. DO NOT FREEZE! Avoid prolonged exposure to light.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD300a

Target: CD300a (CD300A)

Andere Bezeichnung: CD300A / CMRF35H (CD300A Produkte)

Synonyme: CD300L-B1 antikoerper, CD300A antikoerper, clm8 antikoerper, B230315M08Rik antikoerper, Clm8 antikoerper, LMIR1 antikoerper, MAIR-I antikoerper, MAIR-Ia antikoerper, MMAC8 antikoerper, Pigr4 antikoerper, mcpir1 antikoerper, CLM-8 antikoerper, CMRF-35-H9 antikoerper, CMRF-35H antikoerper, CMRF35-H antikoerper, CMRF35-H9 antikoerper, CMRF35H antikoerper, CMRF35H9 antikoerper, IGSF12 antikoerper, IRC1 antikoerper, IRC1/IRC2 antikoerper, IRC2 antikoerper, IRp60 antikoerper, CD300 molecule like family member g antikoerper, CD300a molecule antikoerper, CMRF35-like molecule 8 antikoerper, CD300A molecule antikoerper, Cd300a molecule antikoerper, CD300LG antikoerper, CD300A antikoerper, LOC483289 antikoerper, clm8 antikoerper, Cd300a antikoerper

Hintergrund: CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.Synonyms: CD300 antigen-like family member A, CLM-8, CMRF-35-H9, CMRF35-H, CMRF35-H9, CMRF35-like molecule 8, IRC1/IRC2, IRp60, Inhibitory receptor protein 60, NK inhibitory receptor

Gen-ID: 11314

UniProt: Q9UGN4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process