Mycobacterium Tuberculosis Antigen CFP10 (Rv3874) Antikörper
Kurzübersicht für Mycobacterium Tuberculosis Antigen CFP10 (Rv3874) Antikörper (ABIN238347)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- The polyclonal antibody reacts with CFP10 (LHP), a 12,3 kDa antigen encoded by gene Rv3874 of Mycobacterium tuberculosis. The antibody recognizes CFP10 of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis, it reacts also with recombinant antigen produced in Escherichia coli.
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Aufreinigung
- Protein-A affinity chromatography.
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Immunogen
- CFP10 (Rv3874) of Mycobacterium tuberculosis
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Applikationshinweise
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Suitable for Western Blotting under Reducing conditions: 0.2-1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4 with 15 mM sodium azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Mycobacterium Tuberculosis Antigen CFP10 (Rv3874)
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Andere Bezeichnung
- Cfp10 / EsxB
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Substanzklasse
- Bacteria
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Hintergrund
- CFP10 (10 kDa culture filtrate protein) is a low molecular weight protein isolated from Mycobacterium tuberculosis culture filtrates. CFP10 and the 6 kDa early secretory antigen of T cells (ESAT6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine strain Bacille Calmette Guerin (BCG). CFP10 is one of a small number of secreted M. tuberculosis proteins now identified, that appear to play key roles in tuberculosis pathogenesis and in the stimulation of immunity.Synonyms: 10 kDa culture filtrate antigen cfp10, ESAT-6-like protein esxB, MT3988, MTV027.09, Rv3874, Secreted antigenic protein MTSA-10, lhp, mtsA10
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Gen-ID
- 886194
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NCBI Accession
- NP_218391
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UniProt
- P0A566
Target
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