s100a4 Antikörper

Produktnummer ABIN238333

Produktdetails anti-s100a4 Antikörper

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser s100a4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: Protein G

Immunogen: genetic immunisation with cDNA encoding S100 A4

Klon: NJ-4F3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
ELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Details zu s100a4

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Andere Bezeichnung: S100A4 (S100A4 Produkte)

Synonyme: 18A2 antikoerper, 42A antikoerper, CAPL antikoerper, FSP1 antikoerper, MTS1 antikoerper, P9KA antikoerper, PEL98 antikoerper, 42a antikoerper, Capl antikoerper, FSp1 antikoerper, Mts1 antikoerper, PeL98 antikoerper, metastasin antikoerper, pk9a antikoerper, S100A4 antikoerper, P9ka antikoerper, RNP9KA antikoerper, S100 calcium binding protein A4 antikoerper, S100 calcium-binding protein A4 antikoerper, S100A4 antikoerper, S100a4 antikoerper

Hintergrund: S100 calcium binding protein A4 (S100A4) is a member of the S100 family of calcium-binding proteins that contain two Ca(2+)-binding sites including a canonical EF-hand motif. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells. S100A4 interacts with cytoskeletal proteins and enhances metastasis of several types of cancer cells. It is secreted by unknown mechanisms, thus, paracrinely stimulating a variety of cellular responses, including angiogenesis and neuronal growth. S100A4 has been shown to be a prognostic marker in a number of human cancers, including esophageal-squamous cancers, non-small lung cancers, primary gastric cancers, malignant melanomas, prostate cancers, bladder cancers, and pancreatic carcinomas. The universality of S100A4 expression in a variety of cancers illustrates the potential use of S100A4 as a marker for tumor metastasis and disease progression.

UniProt: P26447

Pathways: S100 Proteine