GDF15 Antikörper (N-Term)
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- Target Alle GDF15 Antikörper anzeigen
- GDF15 (Growth Differentiation Factor 15 (GDF15))
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Bindungsspezifität
- AA 30-194, N-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser GDF15 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Aufreinigung
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding aa30-194 (N-term) of MIC-1 proprotein
- Klon
- ME-6D10
- Isotyp
- IgG1
- Top Product
- Discover our top product GDF15 Primärantikörper
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anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody
Verified GDF15 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Ziege Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibodyGDF15 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB30209 unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (N-Term) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Kommentare
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Synonyms: GDF15
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Andere Bezeichnung
- MIC-1 (GDF15 Produkte)
- Hintergrund
- Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance. MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines. MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours.
- UniProt
- Q99988
- Pathways
- SARS-CoV-2 Protein Interaktom
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