Substance P Antikörper (C-Term)

Produktnummer ABIN230862

Dieses Anti-Substance P-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Substance P in IHC, IHC (p), IHC (fro) und IF. Geeignet für Rind (Kuh).

Kurzübersicht für Substance P Antikörper (C-Term) (ABIN230862)

Target: Substance P

Reaktivität: Rind (Kuh)

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Substance P Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Klon: NC1-34

Produktdetails anti-Substance P Antikörper

Bindungsspezifität: C-Term

Spezifität: Recognizes the COOH terminal end of substance P, a short polypeptide neurotransmitter that regulates the excitability of dorsal horn nociceptive neurons. It is known to have a role in several physiologic activities such as pain transmission, the vomiting reflex, salivary secretion and smooth muscle contraction. 5 % reactivity is observed with eledoisin. It does not react with Leu or Met-enkephalin, somatostatin or beta-endorphin.

Immunogen: Substance P conjugated to Bovine Serum Albumin.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: IF, IHC, IHC-Fr (1:100 - 1:200), IHC-P (1:100 - 1:200)

Usage: Immunohistochemistry: This antibody has been used for the localization of substance P in tissue sections by immunofluorescence and PAP staining in nervous systems of experimental animals and man. Please refer to the Cuello references listed below. It has also been successfully applied in archive post-mortem tissues of the human brain, see Mai and Pioro references.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tissue Culture Supernatant, 0.05 % Thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu Substance P

Target: Substance P

Andere Bezeichnung: TAC1 / Substance P

Hintergrund: Name/Gene ID: TAC1
Family: Hormone

Synonyms: TAC1, Hs.2563, Neurokinin 1, Neurokinin 2, Neuromedin L, Neuropeptide K, NK2, NPK, Protachykinin beta, Protachykinin-1, Substance K, Substance P, Tachykinin, precursor 1, Neurokinin A, Neuropeptide gamma, PPT, Neurokinin alpha, NKA, NKNA, TAC2, Tachykinin 2

Gen-ID: 6863

UniProt: P20366