Ryanodine Receptor Antikörper (C-Term)
Kurzübersicht für Ryanodine Receptor Antikörper (C-Term) (ABIN225614)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Reacts with the C-terminus cytoplasmic domain of ryanodine receptor. Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscle cells. Reacts with ryanodine receptor (MW approx. 500kD) isolated from a variety of cell types (e. g. lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscle, cardiac muscle and brain tissues).
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Aufreinigung
- Purified
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Immunogen
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Short synthetic polypeptide corresponding to the c-terminal domain of the ryanodine receptor.
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG2b
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Applikationshinweise
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Approved: ELISA (1:1000), Flo (1:500), IF (1:100), IHC, IHC-Fr (1:100), WB (1:100)
Usage: Immunohistology: Use indirect immunofluorescence. Visualization by confocal microscopy is required, as detection by standard fluorescent microscopy will not be adequate to detect the RyR. Additionally, fluorescent, not enzymatic, detection is required. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Ryanodine Receptor
Target
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