CRISP3 Antikörper

Produktnummer ABIN2192192

Der Kaninchen Polyklonal Anti-CRISP3-Antikörper wurde für WB, IHC (p) und IA validiert. Er ist geeignet, CRISP3 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für CRISP3 Antikörper (ABIN2192192)

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRISP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoassay (IA)

Produktdetails anti-CRISP3 Antikörper

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Applikationshinweise: For Western blotting and immunohistology dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Referenzen für anti-CRISP3 Antikörper (ABIN2192192)

Udby, Cowland, Johnsen, Sørensen, Borregaard, Kjeldsen: "An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions." in: Journal of immunological methods, Vol. 263, Issue 1-2, pp. 43-55, (2002) (PubMed).

Udby, Calafat, Sørensen, Borregaard, Kjeldsen: "Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils." in: Journal of leukocyte biology, Vol. 72, Issue 3, pp. 462-9, (2002) (PubMed).

Kjeldsen, Cowland, Johnsen, Borregaard: "SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein." in: FEBS letters, Vol. 380, Issue 3, pp. 246-50, (1996) (PubMed).

Details zu CRISP3

Target: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Andere Bezeichnung: Crisp-3

Hintergrund: Cysteine-rich secretory protein 3 (CRISP-3, also known as SGP28) is a glycoprotein that belongs to the family of cysteine-rich secretory proteins (CRISPs) which was originally discovered in human neutrophilic granulocytes. CRISP-3 is also widely distibuted in exocrine glands (salivary glands, pancreas and prostate), eosinophilic granulocytes and to a lower level in epididymis, ovary, thymus and colon. The presence of CRISP-3 in neutrophils, eosinophils and in exocrine secretions indicates a role in innate host defense. The antibody has been raised against recombinant C-terminally truncated form of CRISP-3 and recognizes both the N-glycosylated and non-glycosylated form of the mature protein.