Surfactant Protein B Cross Reactive with Human Sp-B Antikörper

Produktnummer ABIN2192158

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Surfactant Protein B Cross Reactive with Human Sp-B in IA und WB. Es zeigt Reaktivität gegenüber Proben von Schwein. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für Surfactant Protein B Cross Reactive with Human Sp-B Antikörper (ABIN2192158)

Target: Surfactant Protein B Cross Reactive with Human Sp-B

Reaktivität: Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunoassay (IA), Western Blotting (WB)

Produktdetails

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Applikationshinweise: For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Referenzen

Oviedo, Valiño, Plasencia, Serrano, Casals, Pérez-Gil: "Quantitation of pulmonary surfactant protein SP-B in the absence or presence of phospholipids by enzyme-linked immunosorbent assay." in: Analytical biochemistry, Vol. 293, Issue 1, pp. 78-87, (2001) (PubMed).

Pérez-Gil: "Lipid-protein interactions of hydrophobic proteins SP-B and SP-C in lung surfactant assembly and dynamics." in: Pediatric pathology & molecular medicine, Vol. 20, Issue 6, pp. 445-69, (2001) (PubMed).

Antigendetails

Target: Surfactant Protein B Cross Reactive with Human Sp-B

Hintergrund: The polyclonal antibody recognizes the human surfactant protein B (SP-B). There are four surfactant- specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-B is synthesized by the alveolar type II epithelial cells as a 40-42 kD precursor that is subsequently proteolytically processed to 7.8-8 kD. SP-B enhances the spreading and