FABP3 Antikörper

Produktnummer ABIN2191880

Der Maus Monoklonal Anti-FABP3-Antikörper wurde für WB, IP und IA validiert. Er ist geeignet, FABP3 in Proben von Human zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für FABP3 Antikörper (ABIN2191880)

Target: FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FABP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunoassay (IA)

Klon: 66E2

Produktdetails anti-FABP3 Antikörper

Kreuzreaktivität (Details): Cross reactivity: Rat H-FABP : Yes, Mouse H-FABP : Yes, Swine H-FABP : Yes, Human B-FABP Average (in ELISA) Human A-FABP : No, Human I-FABP : No, Human L-FABP : No

Sterilität: 0.2 μm filtered

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.. Positive Heart cells, or recombinant H-FABP control

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Referenzen für anti-FABP3 Antikörper (ABIN2191880)

Zhen, Berna, Jin, Pritt, Watson, Ackermann, Hale: "Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses." in: Proteomics. Clinical applications, Vol. 1, Issue 7, pp. 661-71, (2010) (PubMed).

Zimmermann-Ivol, Burkhard, Le Floch-Rohr, Allard, Hochstrasser, Sanchez: "Fatty acid binding protein as a serum marker for the early diagnosis of stroke: a pilot study." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 1, pp. 66-72, (2004) (PubMed).

Pelsers, Hanhoff, Van der Voort, Arts, Peters, Ponds, Honig, Rudzinski, Spener, de Kruijk, Twijnstra, Hermens, Menheere, Glatz: "Brain- and heart-type fatty acid-binding proteins in the brain: tissue distribution and clinical utility." in: Clinical chemistry, Vol. 50, Issue 9, pp. 1568-75, (2004) (PubMed).

Guillaume, Zimmermann, Burkhard, Hochstrasser, Sanchez: "A potential cerebrospinal fluid and plasmatic marker for the diagnosis of Creutzfeldt-Jakob disease." in: Proteomics, Vol. 3, Issue 8, pp. 1495-9, (2003) (PubMed).

Roos, Eymann, Symannek, Duppenthaler, Wodzig, Pelsers, Glatz: "Monoclonal antibodies to human heart fatty acid-binding protein." in: Journal of immunological methods, Vol. 183, Issue 1, pp. 149-53, (1995) (PubMed).

Details zu FABP3

Target: FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))

Andere Bezeichnung: Fatty Acid-Binding Protein, Heart

Hintergrund: The monoclonal antibody 66E2 recognizes human heart-type fatty acid-binding protein (H-FABP) of both natural and recombinant origin. The H-FABP protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary. It is also useful as marker for brain damage. Furthermore, this antibody is useful for the purification of H-FABP. Aliases Fatty acid-binding protein 3, FABP3, Muscle fatty acid-binding protein, Mammary-derived growth inhibitor Immunogen Purified human H-FABP

Pathways: Monocarboxylic Acid Catabolic Process