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LRG1 Antikörper

LRG1 Reaktivität: Human IA, WB Wirt: Maus Monoclonal 2F5-A2 unconjugated
Pubmed (1 reference)
Produktnummer ABIN2191876
$547.49
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle LRG1 Antikörper anzeigen
    LRG1
    Reaktivität
    • 71
    • 9
    • 8
    • 2
    • 1
    • 1
    Human
    Wirt
    • 59
    • 17
    • 1
    Maus
    Klonalität
    • 54
    • 23
    Monoklonal
    Konjugat
    • 50
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser LRG1 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 27
    • 23
    • 13
    • 10
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunoassay (IA), Western Blotting (WB)
    Sterilität
    0.2 μm filtered
    Klon
    2F5-A2
  • Applikationshinweise
    and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Codina, Vanasse, Kelekar, Vezys, Jemmerson: "Cytochrome c-induced lymphocyte death from the outside in: inhibition by serum leucine-rich alpha-2-glycoprotein-1." in: Apoptosis : an international journal on programmed cell death, Vol. 15, Issue 2, pp. 139-52, (2010) (PubMed).

  • Target
    LRG1
    Andere Bezeichnung
    Leucine-Rich alpha-2-Glycoprotein (LRG1 Produkte)
    Synonyme
    lrg, HMFT1766, LRG, 1300008B03Rik, 2310031E04Rik, Lrg, Lrhg, si:dkey-90m5.4, leucine rich alpha-2-glycoprotein 1, leucine-rich alpha-2-glycoprotein 1 L homeolog, leucine-rich alpha-2-glycoprotein 1, perilipin-5, si:dkey-90m5.4, LRG1, lrg1.L, Lrg1, PLIN5
    Hintergrund
    The monoclonal antibody recognizes leucine-rich alpha-2-glycoprotein (LRG), a member of the leucine- rich repeat family. LRG is a plasma protein of approximately 50 kDa. LRG consists of 312 amino acids. It has 1 galactosamine and 4 glucosamine oliogosacharides attached and has 2 intrachain disulfide bonds. Leucine comprises 66 of the 312 amino acids, and LRG contains at least eight 24-amino acid leucine-rich repeats. The consensus of these residues, termed leucine-rich repeats (LRR), has been identified as an LRR-containing domain. The primary function of LRRs is to provide versatile structural framework of the formation of protein-protein interactions. LRG is expressed during granulocyte differentiation. Although several family members of the leucine-rich repeat family have been shown to be involved in signal transduction, protein-protein interaction, or cell adhesion and development, a function for LRG remains elusive. LRG has been reported as a biomarker for certain diseases including microbial infections and cancer. LRG can be detected in human neutrophils and progenitor cells, but not in peripheral blood mononuclear cells. The monoclonal antibody 2F5.A2 can be used for immuno purification of human LRG. Aliases Leucine-rich alpha-2-glycoprotein, LRG Immunogen Human LRG, covalently coupled to hemocyanin using glutaraldehyde
    Pathways
    Brown Fat Cell Differentiation
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