BCR Antikörper (pTyr177)
Kurzübersicht für BCR Antikörper (pTyr177) (ABIN219125)
Target
Alle BCR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr177
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Spezifität
- Recognizes endogenous levels of human Bcr and Bcr-Abl only when phosphorylated at tyrosine 177. Species cross-reactivity: Mouse.
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Aufreinigung
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Tyr177 of human Bcr. Molecular Weight:160kD (Bcr), 210kD (Bcr-Abl).
Type of Immunogen: Synthetic phospho-peptide -
Isotyp
- IgG
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Applikationshinweise
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Approved: Flo (1:50), IHC, IHC-P, WB (1:1000)
Usage: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:50. Flow Cytometry: 1:50. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- BCR (Breakpoint Cluster Region (BCR))
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Andere Bezeichnung
- CML / BCR
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Hintergrund
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Name/Gene ID: BCR
Subfamily: BCR
Family: Protein Kinase
Synonyms: BCR, Acute lymphocytic leukemia, ALL, BCR1, BCR/FGFR1 chimera protein, Breakpoint cluster region, Chronic myeloid leukemia, D22S11, CML, D22S662, Philadelphia chromosome, PHL, FGFR1/BCR chimera protein -
Molekulargewicht
- 160kDa (Bcr), 210kDa (Bcr-Abl).
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Gen-ID
- 613
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UniProt
- P11274
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Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
Target
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