Superoxide dismutase copper chaperone Antikörper (AA 201-274)

Produktnummer ABIN2179351

Produktdetails anti-Superoxide dismutase copper chaperone Antikörper

Target: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Bindungsspezifität: AA 201-274

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Superoxide dismutase copper chaperone Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOD4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Superoxide dismutase copper chaperone

Target: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Andere Bezeichnung: SOD4/CCS (CCS Produkte)

Synonyme: ccs antikoerper, MGC82563 antikoerper, CCS antikoerper, DDBDRAFT_0189222 antikoerper, DDBDRAFT_0238038 antikoerper, DDB_0189222 antikoerper, DDB_0238038 antikoerper, ATCCS antikoerper, COPPER/ZINC SUPEROXIDE DISMUTASE COPPER CHAPERONE antikoerper, F5O11.26 antikoerper, F5O11_26 antikoerper, copper chaperone for SOD1 antikoerper, Ccsd antikoerper, copper chaperone for superoxide dismutase L homeolog antikoerper, copper chaperone for superoxide dismutase antikoerper, copper chaperone for SOD1 antikoerper, ccs.L antikoerper, ccs antikoerper, CCS antikoerper, LOC552629 antikoerper, Ccs antikoerper

Hintergrund:

Synonyms: CCS, CCS_HUMAN, Copper chaperone for superoxide dismutase, MGC138260, SOD 4, SOD4, Superoxide dismutase copper chaperone.

Background: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

Gen-ID: 9973

Pathways: Transition Metal Ion Homeostasis