SHROOM1 Antikörper (AA 121-220) (Biotin)

Produktnummer ABIN2179203

Dieses Anti-SHROOM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SHROOM1 in ELISA, IHC (fro) und IHC (p). Geeignet für Human.

Kurzübersicht für SHROOM1 Antikörper (AA 121-220) (Biotin) (ABIN2179203)

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHROOM1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SHROOM1 Antikörper (Biotin)

Bindungsspezifität: AA 121-220

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SHROOM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SHROOM1

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Andere Bezeichnung: SHROOM1

Hintergrund:

Synonyms: Apical protein 2, APXL2, Protein Shroom1, SHRM1_HUMAN, Shroom family member 1, Shroom1.

Background: SHROOM1 is an 852 amino acid protein that contains one ASD1 domain and one ASD2 domain. Localized to both the cytoplasm and the cytoskeleton, SHROOM1 interacts with Actin and is thought to be involved in microtubule assembly during cell elongation, possibly playing a role in the development of the nervous system. Multiple isoforms of SHROOM1 exist due to alternative splicing events. The gene encoding SHROOM1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.