INTU Antikörper (Cy3)

Produktnummer ABIN2178390

Dieses Anti-INTU-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von INTU in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für INTU Antikörper (Cy3) (ABIN2178390)

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INTU Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB)

Produktdetails anti-INTU Antikörper (Cy3)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDZD6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Andere Bezeichnung: PDZD6

Hintergrund:

Synonyms: Protein inturned, Inturned planar cell polarity effector homolog, PDZ domain-containing protein 6, INTU, KIAA1284, PDZD6, PDZK6, INTU_HUMAN.

Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

Gen-ID: 27152

UniProt: Q9ULD6