MAP4K4 Antikörper (pSer629) (PE)

Produktnummer ABIN2177518

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAP4K4 in FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MAP4K4 Antikörper (pSer629) (PE) (ABIN2177518)

Target: MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP4K4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MAP4K4 Antikörper (PE)

Bindungsspezifität: pSer629

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C for 12 months.

Details zu MAP4K4

Target: MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

Andere Bezeichnung: Map4k4

Hintergrund: MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.
Synonyms: MAP4K4phospho S629, Hepatocyte progenitor kinase like/germinal center kinase like kinase, HGK, HPK/GCK like kinase, HPK/GCK like kinase HGK, KIAA0687, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, Mitogen activated protein kinase kinase kinase kinase 4, Nck interacting kinase, NIK.

Gen-ID: 9448