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MAGI1 Antikörper (AA 161-260) (Alexa Fluor 488)

MAGI1 Reaktivität: Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN2177494
$470.46
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle MAGI1 Antikörper anzeigen
    MAGI1 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 161-260
    Reaktivität
    • 29
    • 16
    • 3
    Ratte
    Wirt
    • 39
    • 4
    Kaninchen
    Klonalität
    • 41
    • 2
    Polyklonal
    Konjugat
    • 15
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAGI1 Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 27
    • 22
    • 14
    • 12
    • 12
    • 6
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MAGI1
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    MAGI1 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1))
    Andere Bezeichnung
    MAGI1/IRSP58 (MAGI1 Produkte)
    Synonyme
    CNKSR3 antikoerper, AIP-3 antikoerper, AIP3 antikoerper, BAIAP1 antikoerper, BAP-1 antikoerper, BAP1 antikoerper, MAGI-1 antikoerper, TNRC19 antikoerper, WWP3 antikoerper, Baiap1 antikoerper, Gukmi1 antikoerper, MAGI1c antikoerper, Magi-1 antikoerper, mKIAA4129 antikoerper, membrane associated guanylate kinase, WW and PDZ domain containing 1 antikoerper, MAGI1 antikoerper, Magi1 antikoerper
    Hintergrund

    The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains, however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.

    Subcellular location: Cell membrane

    Synonyms: AIP 3, AIP3, Atrophin 1 interacting protein 3, atrophin-1 interacting protein 3, BAI associated protein 2, BAI1 associated protein 1, BAI1-associated protein 1, BAIAP 1, BAIAP1, BAP 1, BAP1, BAP2, Brain specific angiogenesis inhibitor 1 associated protein 2, Fas ligand associated factor 3, FLAF3,Gukmi1, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, IRS 58, IRSP53, IRSp53/58, MAGI 1, MAGI-1, MAGI1c, Membrane associated guanylate kinase inverted 1, membrane associated guanylate kinase inverted-1, membrane associated guanylate kinase WW and PDZ domain containing 1, Protein BAP2, TNRC 19, TNRC19, Trinucleotide repeat containing gene 19, Trinucleotide repeat containing gene 19 protein,trinucleotide repeat-containing gene 19, WW domain containing protein 3, WW domain-containing protein 3, WWP 3, WWP3.

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