LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) Antikörper (FITC)

Produktnummer ABIN2177323

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) Antikörper (FITC) (ABIN2177323)

Target: LIM Domain Kinase 1/2 (LIMK1/2)

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails

Bindungsspezifität: pThr505

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: LIM Domain Kinase 1/2 (LIMK1/2)

Andere Bezeichnung: LIMK1LIMK2

Hintergrund:

Synonyms: LIMK1Thr508, EC 2.7.11.1, LIM domain kinase 1, LIM mot-containing protein kinase, LIMK, LIMK-1, LIMK2, LIMK-2, LIM domain kinase 2, LIMK1_HUMAN.

Background: LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development, it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.

Gen-ID: 3984