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FAM48A/P38IP Antikörper (AA 21-120) (Cy5)

SUPT20H Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN2174053
  • Target Alle FAM48A/P38IP (SUPT20H) Antikörper anzeigen
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 19
    • 3
    • 2
    Human
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAM48A/P38IP Antikörper ist konjugiert mit Cy5
    Applikation
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FAM48A
    Isotyp
    IgG
    Top Product
    Discover our top product SUPT20H Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    Andere Bezeichnung
    Fam48a (SUPT20H Produkte)
    Synonyme
    SUPT20H antikoerper, AA667204 antikoerper, AI450544 antikoerper, D3Ertd300e antikoerper, Fam48a antikoerper, Supt20h antikoerper, p38IP antikoerper, RGD1307812 antikoerper, C13 antikoerper, C13orf19 antikoerper, FAM48A antikoerper, P38IP antikoerper, SPT20 antikoerper, bA421P11.4 antikoerper, SPT20 homolog, SAGA complex component antikoerper, suppressor of Ty 20 antikoerper, SUPT20H antikoerper, Supt20 antikoerper, Supt20h antikoerper
    Hintergrund

    Synonyms: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

    Background: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

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