Human Papilloma Virus E7 (HPV E7) (Middle Region) Antikörper (Cy5)

Produktnummer ABIN2173802

Der Kaninchen Polyklonal anti-Human Papilloma Virus E7 Antikörper wird verwendet zum Nachweis von Human Papilloma Virus E7 in Proben von Human Papillomavirus 16 (HPV-16). Er wurde validiert für WB, FACS, IF (cc) und IF (p).

Kurzübersicht für Human Papilloma Virus E7 (HPV E7) (Middle Region) Antikörper (Cy5) (ABIN2173802)

Target: Human Papilloma Virus E7 (HPV E7)

Reaktivität: Human Papillomavirus 16 (HPV-16)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Cy5

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails

Bindungsspezifität: Middle Region

Spezifität: This antibody may also detect HPV35-E7

Kreuzreaktivität: Human, Virus

Kreuzreaktivität (Details): HPV16

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from middle of HPV16-E7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Human Papilloma Virus E7 (HPV E7)

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: Protein E7, E7

Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

Gen-ID: 1489079

UniProt: P03129