GDF5 Antikörper

Produktnummer ABIN217376

Der Ratte Monoklonal Anti-GDF5-Antikörper wurde für ELISA, Neut und Func validiert. Er ist geeignet, GDF5 in Proben von Maus zu detektieren.

Kurzübersicht für GDF5 Antikörper (ABIN217376)

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser GDF5 Antikörper ist unkonjugiert

Applikation: ELISA, Neutralization (Neut), Functional Studies (Func)

Produktdetails anti-GDF5 Antikörper

Spezifität: Recognizes mouse GDF-5 in direct ELISA. Does not cross-react with rmGDF-1, rmGDF-3, or rmGDF-8.

Aufreinigung: Protein G purified

Immunogen: E. coli-derived monomeric rmGDF-5.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 - 1 μg/mL), Func, Neut

Usage: Suitable for use in direct ELISA and Neutralization. Neutralization (ND50): ~2-10 μg/mL in the presence of 3 μg/mL of rmGDF-5, using the ATDC5 cell line. Note: The exact concentration of antibody required to neutralize rmGDF-5 activity is dependent on the cytokine concentration, cell type, growth conditions and the type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. Direct ELISA: 0.5-1.0 μg/mL. The detection limit is ~10 ng/well.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Sterile PBS

Konzentration: Lot specific

Buffer: Lyophilized from PBS, 5 % trehalose.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C lyophilized. Once reconstituted, aliquot and store at -20°C.

Details zu GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: GDF5 / GDF-5

Hintergrund: Name/Gene ID: GDF5
Family: TGF beta

Synonyms: GDF5, CDMP-1, CDMP1, GDF-5, LAP4, Radotermin, OS5, BMP14, SYNS2

Gen-ID: 8200

UniProt: P43026