Claudin 16 Antikörper (AA 95-150) (AbBy Fluor® 647)
Kurzübersicht für Claudin 16 Antikörper (AA 95-150) (AbBy Fluor® 647) (ABIN2173139)
Target
Alle Claudin 16 (CLDN16) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 95-150
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Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Claudin 16
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Claudin 16 (CLDN16)
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Andere Bezeichnung
- Claudin 16
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Hintergrund
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Synonyms: HOMG3, PCLN1, Claudin-16, Paracellin-1, PCLN-1, CLDN16
Background: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.
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Gen-ID
- 10686
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UniProt
- Q9Y5I7
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Pathways
- Hepatitis C
Target
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