B3GALNT1 Antikörper (AA 231-331) (Biotin)

Produktnummer ABIN2170471

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch B3GALNT1 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für B3GALNT1 Antikörper (AA 231-331) (Biotin) (ABIN2170471)

Target: B3GALNT1 (beta-1,3-N-Acetylgalactosaminyltransferase 1 (B3GALNT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser B3GALNT1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-B3GALNT1 Antikörper (Biotin)

Bindungsspezifität: AA 231-331

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human B3GALNT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu B3GALNT1

Target: B3GALNT1 (beta-1,3-N-Acetylgalactosaminyltransferase 1 (B3GALNT1))

Andere Bezeichnung: B3GALNT1

Hintergrund:

Synonyms: 3-galactosyltransferase 3, 3-GalNAc-T1, 3-GalTase 3, 3-N-acetylgalactosaminyltransferase 1, 3-N-acetylgalactosaminyltransferase, b3Gal T3, b3Gal-T3, B3galnt1, B3GALT3, B3GL1_HUMAN, Beta 1,3 galactosyltransferase 3, Beta 1,3 GalTase 3, beta 1,3 N acetylgalactosaminyltransferase 1 globoside blood group, Beta 3 GalNAc T1, Beta 3 Gx T3, Beta-1, Beta-3-Gx-T3, beta3Gal T3, Beta3Gal-T3, Beta3GalT3, brainiac1, Galactosylgalactosylglucosylceramide beta D acetyl galactosaminyltransferase, Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase, galT3, Gb4Cer, GLCT3, GLOB, Globoside synthase, globotriaosylceramide 3 beta N acetylgalactosaminyltransferase, P antibody P antigen synthase, P blood group globoside, P1 antibody UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase 1, UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase, polypeptide 3 Globoside blood group, UDP GalNAc:beta 1,3 N acetylgalactosaminyltransferase 1, UDP GalNAc:betaGlcNAc beta 1,3 galactosaminyltransferase, polypeptide 1 Globoside blood group, UDP N acetylgalactosamine:globotriaosylceramide beta 1,3 N acetylgalactosaminyltransferase, UDP-GalNAc:beta-1, UDP-N-acetylgalactosamine:globotriaosylceramide beta-1

Background: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described, they all encode the same protein.

Gen-ID: 8706

UniProt: O75752