BAF53A Antikörper (AA 331-406)

Produktnummer ABIN2170317

Dieses Anti-BAF53A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BAF53A in WB, ELISA und IHC (p). Geeignet für Maus.

Kurzübersicht für BAF53A Antikörper (AA 331-406) (ABIN2170317)

Target: BAF53A (Actin-Like 6A (BAF53A))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAF53A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BAF53A Antikörper

Bindungsspezifität: AA 331-406

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANGPTL4/ARP4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BAF53A

Target: BAF53A (Actin-Like 6A (BAF53A))

Andere Bezeichnung: ARP4

Hintergrund:

Synonyms: Angiopoietin like 4, Angiopoietin related protein 4, Angiopoietin-like protein 4, Angiopoietin-related protein 4, Angiopoietin-like 4, ANGL4_HUMAN, ANGPT L2, ANGPT L4, ANGPTL2, ANGPTL4, ARP4, Fasting induced adipose factor, FIAF, Hepatic angiopoietin related protein, Hepatic fibrinogen/angiopoietin related protein, Hepatic fibrinogen/angiopoietin-related protein, HFARP, NL2, Peroxisome prolerator-activated receptor PPAR gamma induced angiopoietin related protein antibody PGAR, pp1158, PPARG angiopoietin related protein, PSEC0166, Weakly similar to angiopoietin 1 [H.sapiens].

Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Gen-ID: 51129

Pathways: Chromatin Binding, Photoperiodism