BAZ1A Antikörper (PE)

Produktnummer ABIN2169796

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BAZ1A in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für BAZ1A Antikörper (PE) (ABIN2169796)

Target: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAZ1A Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB)

Produktdetails anti-BAZ1A Antikörper (PE)

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP utilizing chromatin assembly and remodeling factor 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Details zu BAZ1A

Target: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Andere Bezeichnung: Acf1

Hintergrund:

Synonyms: BAZ1A, Acf1, ACF1, drosophila, homolog of antibody ATP dependent chromatin remodelling protein, ATP utilizing chromatin assembly and remodeling factor 1, ATP-dependent chromatin-remodeling protein, ATP-utilizing chromatin assembly and remodeling factor 1, Baz1a, BAZ1A_HUMAN, Bromodomain adjacent to zinc finger domain 1A, Bromodomain adjacent to zinc finger domain protein 1A, cbp146, CHRAC subunit ACF1, Gtl5.

Background: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.

Gen-ID: 11177

UniProt: Q9NRL2